Skin care

Niche Skincare: Why Twelve Beauty Is Redefining the Rules

Twelve Beauty Niche Skincare

In a world full of fleeting skincare trends and mass-market formulas, niche skincare has become the go-to choice for those seeking real results, clean ingredients, and integrity. At Twelve Beauty, we don’t just participate in this movement – we’re one of its originators.

Since day one, our mission has been clear: to create intelligent, skin-kind formulas that support, protect and restore even the most sensitive skin. We’re proud to be part of the growing niche skincare space, but even more proud to say we’ve helped shape it.

Here’s what niche skincare means to us – and why Twelve Beauty continues to break the mould.

What Is Niche Skincare?

Niche skincare refers to formulas designed with precision, intention, and purpose. Unlike mainstream skincare – which often prioritises marketing and mass appeal – niche skincare puts real skin needs first. It’s focused, often founder-led, and built on expertise rather than trends.

At Twelve Beauty, that focus is sensitive, stressed and reactive skin. Over 60% of our customers report having delicate or compromised skin, and we formulate with them in mind every step of the way.

For us, niche skincare isn’t a passing trend – it’s the foundation of everything we do.

Rewarding Body Balm Twelve Beauty

Our Origins: Skincare with Heart

Our founder, Pedro Catalá, began Twelve Beauty with a very specific purpose: to create deeply effective, gentle skincare that supported the needs of patients undergoing cancer treatments. While working as a pharmacist at a clinic on London’s Harley Street, Pedro saw firsthand the devastating toll chemotherapy and radiotherapy could take on the skin – intense dryness, inflammation, and even pain from wearing clothes.

It was clear something had to change.

That’s why Pedro created our first-ever product: Rewarding Body Balm, formulated to soothe, hydrate and restore fragile skin. Originally developed for oncology patients, the balm is now used in private clinics across London and remains a cornerstone of our range. It also marked the start of our journey into truly pioneering niche skincare.

Our Philosophy: Clean, Botanical Science for Delicate Skin

We believe skincare should support the skin’s structure – not fight against it. That’s why we fuse clean botanical ingredients with skin-safe science to deliver formulas that work in harmony with the skin’s natural functions.

All of our products are:

  • 100% plant-based
  • Made with ECO-approved ingredients
  • Rich in actives from organic and sustainable sources
  • Developed using strict green chemistry processes
  • Every ingredient we include is there for a reason – and brings a benefit to the skin, no matter its role.

We don’t use anything that could compromise sensitive skin – not even commonly accepted “natural” ingredients that have a history of causing allergic reactions. Every product we create is grounded in Pedro’s expertise in pharmacology and botany, designed to be as effective as it is kind.

This is niche skincare with purpose.

formulating niche skincare

We Don’t Follow Trends. We Set Them.

Since the beginning, we’ve pushed the boundaries of what skincare can do – often introducing innovations that the industry hadn’t seen before. Here are just a few ways we’ve led the way in niche skincare:

  • Purifying Cleansing Beauty Cream: We were the first to blend high doses of plant-based squalane into a rinse-off cleanser, helping skin stay nourished, even during cleansing.
  • Hyaluroil Lip Treatment: Launched in 2015, this was the first lip oil of its kind to encapsulate short-chain hyaluronic acid for deep hydration and a plumper appearance.
  • Rewarding Body Balm: One of the first body care products to incorporate high-performance skincare actives traditionally used in facial care, setting a new standard for intelligent hydration.
  • Nutritive Repair Emulsion: Long before “upcycling” became mainstream, we have been using spent grain wax (a by-product of the malt industry) to naturally regenerate the skin barrier since 2005.
  • Rapid Eye Treatment: A pioneering eye treatment that uses plant-based peptides to visibly firm and revitalise the delicate eye area. We were the first ones to introduce natural peptides in eye care.
  • Intelligent Frontier Facial Oil: A breakthrough formula powered by unsaponifiable plant oils—rare, costly, and notoriously difficult to formulate with, despite being known since the 1950s. These precious oils boost essential lipids and ceramides, visibly strengthening the skin barrier for greater resilience.

Every formula we launch is a step forward for niche skincare – backed by science, powered by nature, and designed for skin that needs more than just surface-level results.

Who We Formulate For

Twelve Beauty was created for sensitive souls – literally. But our formulations also serve a much wider audience seeking skincare that’s gentle yet effective. Our products are especially suitable for:

  • Skin that’s fine-textured, dry, or prone to breakouts
  • Skin that reacts to temperature changes (hot or cold)
  • Skin exposed to environmental stress (pollution, wind, sun)
  • Skin undergoing hormonal shifts
  • Skin affected by medication, illness, or emotional stress
  • Skin with a predisposition to allergic reactions

Our customers are looking for something more than just another moisturiser. They want niche skincare that understands the needs of real skin – and supports it at every stage of life.

sensitive skin skincare

Botanicals Meet Science

What makes Twelve Beauty truly unique is our fusion of two worlds: plant-based ingredients and scientific rigour. Pedro’s background in pharmacy and botany allows him to select the most potent natural actives – then combine them in ways that are both safe and effective.

We test every formula not just for results, but for skin compatibility. The result? Products that are powerful yet gentle. Luxurious yet functional. Visible results while minimising the risk of irritation.

92% of participants in our most recent clinical study reported firmer, smoother, and clearer skin after just four weeks. That’s the kind of efficacy we stand behind – and it’s exactly what niche skincare should deliver.

Small Batches, Big Impact

One of the most defining traits of true niche skincare is small-batch production – and at Twelve Beauty, it’s a principle we live by. Every formulation is made in limited quantities under the direct supervision of our founder, ensuring unmatched freshness, quality, and consistency. This careful curation means our products reach the shelves at their peak, with active ingredients at their most potent and formulas at their most effective. It also allows us to respond swiftly to feedback, make thoughtful improvements, and maintain full control over what goes into every bottle and jar. With Twelve Beauty, you’re not just buying skincare – you’re receiving something crafted with intention, integrity, and attention to every detail.

niche skincare in house laboratory

Why Niche Skincare Matters More Than Ever

In today’s beauty landscape, where fast launches and viral trends dominate the conversation, niche skincare offers something deeper: integrity. It’s not about overcomplicating your routine or chasing the next big thing. It’s about listening to your skin – and responding with care.

At Twelve Beauty, we’re proud to be part of this movement. We believe in skincare that is simple, functional, and grounded in science. Skincare that doesn’t just look good on the shelf – but actually makes a difference to your skin.

Join the Skincare Quiet Revolution

We’re not here to be loud – we’re here to be effective. If you’re ready to leave behind the noise of conventional beauty and embrace a more meaningful approach, discover Twelve Beauty. Experience the power of niche skincare that respects your skin and your wellbeing.

Because skincare should never be about convincing you to buy more – it should be about helping your skin become its best, most balanced self.

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